Zinzino BalanceOil

Zinzino BalanceOil: A key component of our nutritional strategy

We recognize the critical role that inflammation plays in the development and progression of cardiovascular disease. A significant factor in managing this inflammation is achieving a healthy balance between omega-3 and omega-6 fatty acids in your diet.

Modern Western diets often have a dramatically skewed omega-6 to omega-3 ratio, sometimes as high as 15:1 or even 30:1. This imbalance can contribute to a state of chronic, low-grade systemic inflammation, which is detrimental to cardiovascular health. Zinzino BalanceOil is specifically formulated to help you rebalance this crucial ratio, promoting a more anti-inflammatory environment within your body.

How does Zinzino BalanceOil work to reduce systemic inflammation?

Zinzino BalanceOil is a unique blend of natural fish oil (rich in EPA and DHA, key omega-3s) and high-polyphenol extra virgin olive oil. The science behind its efficacy lies in several key mechanisms:

Optimizing the Omega-3:6 Ratio: The primary goal is to shift your body’s fatty acid profile towards a healthier balance. Omega-3 fatty acids, particularly EPA and DHA, are precursors to powerful anti-inflammatory molecules called resolvins and protectins. Conversely, an excess of omega-6 fatty acids can lead to the production of pro-inflammatory mediators. By increasing your omega-3 intake and improving the ratio, Zinzino BalanceOil helps to dampen inflammatory pathways.

Polyphenol Synergy: The high-polyphenol olive oil in BalanceOil plays a crucial synergistic role. Polyphenols are potent antioxidants that protect the delicate omega-3 fatty acids from oxidation both in the bottle and within your body, ensuring their bioavailability and effectiveness. Furthermore, olive oil polyphenols themselves possess anti-inflammatory properties, contributing to the overall reduction in systemic inflammation.

Cellular Membrane Integration: When consumed regularly, the omega-3 fatty acids from BalanceOil become incorporated into the phospholipid membranes of your cells, including those in your blood vessels and heart. This alters the cellular environment, making cells less prone to inflammatory responses and more receptive to anti-inflammatory signals.

Evidence Supporting the Use of Omega-3s and Omega-3:6 Ratio Improvement for Cardiovascular Health and Inflammation:

Numerous studies underscore the importance of omega-3 fatty acids and a balanced omega-3:6 ratio in cardiovascular health:

• Reduction of Inflammatory Markers: Research has consistently shown that omega-3 supplementation can significantly reduce levels of inflammatory markers such as C-reactive protein (CRP), interleukin-6 (IL-6), and tumour necrosis factor-alpha (TNF-α), all of which are implicated in cardiovascular disease progression. (See: Calder, P. C. (2017). Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochemical Society Transactions, 45(5), 1105-1115.)
• Endothelial Function Improvement: Omega-3 fatty acids contribute to improved endothelial function, the health of the inner lining of your blood vessels. This is crucial for preventing atherosclerosis and maintaining healthy blood flow. (See: Mason, R. P., Libby, P., & Bhatt, D. L. (2020). Emerging mechanisms of cardiovascular protection for the omega-3 fatty acid eicosapentaenoic acid. Arteriosclerosis, Thrombosis, and Vascular Biology, 40(5), 1135-1149.)
• Reduced Risk of Cardiovascular Events: Large-scale epidemiological studies and clinical trials have demonstrated that higher intake of omega-3 fatty acids is associated with a reduced risk of major adverse cardiovascular events, including heart attacks and strokes. While more recent trials have nuanced the picture for primary prevention in the general population, for patients with established cardiovascular disease, the benefits of targeted omega-3 supplementation are more pronounced. (See: Bhatt, D. L., et al. (2019). Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia. New England Journal of Medicine, 380(1), 11-22. – This study, while focusing on a pharmaceutical-grade omega-3, highlights the powerful cardiovascular benefits of EPA.)
• Importance of the Omega-3:6 Ratio: The concept of the omega-3:6 ratio is increasingly recognized as a crucial determinant of inflammatory status. A lower ratio is generally associated with a more pro-inflammatory state. (See: Simopoulos, A. P. (2016). An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity. Nutrients, 8(3), 128. While this focuses on obesity, the underlying inflammatory mechanisms are highly relevant to cardiovascular disease.)

At our clinic, we utilise a unique, accurate dried blood spot test to measure your current omega-3:6 ratio and other fatty acid profiles, allowing us to precisely tailor your Zinzino BalanceOil dosage and monitor your progress. This personalised approach ensures you achieve optimal levels for reduced systemic inflammation and enhanced cardiovascular well-being.

We are committed to providing you with the most effective strategies to protect and restore your heart health. Speak with our team today to learn more about how Zinzino BalanceOil can be a vital part of your cardiac care plan.